Opinion

Ideas, arguments and debate

Evidence-aware viewpoints on the questions, uncertainties and future direction of liver critical care.

Opinion

Is there a role for NAC outside of paracetamol overdose?

NAC is routine in paracetamol toxicity. Joe Wilson examines the much less certain evidence for its use in non-paracetamol acute liver failure, decompensated cirrhosis, severe alcohol-related hepatitis and critical illness.

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Editorial

Is ARDS 10-15 years ahead of ACLF?

ARDS has had decades to learn that a useful syndrome definition does not make a biologically uniform disease. ACLF is now facing many of the same questions. If ARDS is ahead, it offers both a roadmap and a warning.

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